"An Education," "The Hurt Locker," "Inglourious Basterds," "Nine" and "Precious" took the SAG nominations for best ensemble cast.
Michelle Monaghan and Chris O'Donnell announced the nominations Thursday morning at the Pacific Design Center in West Hollywood.
Nominees for best actor were Jeff Bridges for "Crazy Heart," George Clooney for "Up in the Air," Colin Firth for "Single Man," Morgan Freeman for "Invictus" and Jeremy Renner for "The Hurt Locker."
Actress noms went to Sandra Bullock for "The Blind Side," Helen Mirren for "The Last Station," Carey Mulligan for "An Education," Gabourey Sidibe for "Precious" and Meryl Streep for "Julie and Julia."
Supporting actor nods went to Matt Damon for "Invictus," Woody Harrelson for "The Messenger," Christopher Plummer for "The Last Station," Stanley Tucci for "The Lovely Bones" and Christop Waltz for "Inglourious Basterds."
Supporting actress noms included Penelope Cruz for "Nine," Vera Farmiga and Anna Kendrick for "Up in the Air," Diane Kruger for "Inglourious Basterds" and Mo'Nique for "Precious."
Winners will be announced Jan. 23 in ceremonies at the Shrine Auditorium in Los Angeles.
Ballots will be sent to the 120,000 members of the Screen Actors Guild.
The SAG award for best ensemble cast has matched the Oscar winner for Best Picture in seven of the last 14 years, including this year's double winner "Slumdog Millionaire."
SAG's best actor winner has matched the Oscar winner in 11 of the last 15 years, including Sean Penn for "Milk" this year.
SAG's best actress winner has matched the Oscar in 10 of 15 years. Streep won the SAG trophy this year for "Doubt" and Kate Winslet won the Oscar for "The Reader" after winning the SAG prize in the supporting category.